GenoPro Support Forum

I have recently found this great program and have a few questions.

 

We work with canine genetics and our goal is to map new disease genes for various inherited diseases in dogs. One method we use, is linkage analysis and therefore we need linkage files from our pedigrees like this:

 

1 1 0 0 1 1 0 0 0
1 2 0 0 2 2 0 0 2
1 3 0 0 2 1 0 0 2
1 4 0 0 1 2 0 0 2
1 5 0 0 2 1 0 0 2
1 6 1 2 1 1 0 0 2
1 7 1 2 2 2 0 0 2
1 8 0 0 1 1 0 0 2
1 9 0 0 2 1 0 0 2
1 10 4 3 2 1 0 0 2
1 11 4 3 1 2 0 0 2
1 12 4 3 1 2 0 0 2
1 13 4 5 1 1 0 0 2
1 14 0 0 1 1 0 0 0
1 15 8 7 2 2 0 0 2
1 16 8 7 2 2 0 0 2
1 17 8 7 2 2 0 0 2
1 18 8 7 2 2 0 0 2
1 19 8 7 2 1 0 0 2
1 20 8 9 1 1 0 0 2
1 21 8 9 2 2 0 0 2
1 22 8 10 2 2 0 0 2
1 23 8 10 1 2 0 0 2
1 24 8 10 1 1 0 0 2
1 25 14 29 1 2 0 0 2
1 26 14 29 2 1 0 0 2
1 27 14 29 2 2 0 0 2
1 28 14 29 2 2 0 0 2

 

First number is the family number, second individual number, third is the id of father, 4th the id of mother, 5th gender (1= male, 2=female), 6th disease (0=unknown, 1=healthy, 2=ill), 7th and 8th loci 1 alleles and 9th DNA (0=not available, 2=available for genotyping). This is an example of data needed for simulation the data with SLINK. Would it be possible to generate directly this kind of file from the pedigree and vice versa?

 

The availability of DNA would be nice to see somehow on pedigree picture.

 

After genotyping, the alleles would be nice to see in pedigree, maybe under the gender symbol...

 

My collague wishes a data field for dog registration number and was also wondering, if it is possible to adjust the affected symbol so, that instead of the "plus-sign" the symbol would be black?

 

Hope you understand my english...

 

Best regards,

Paivi